tool compound造句
例句與造句
- Several are sources of important natural products pharmacologic tool compounds and drug research candidates, and in some cases actual prescription drugs.
- TTX and its analogs have historically been important agents for use as chemical tool compounds, for use in channel characterization and in fundamental studies of channel function.
- While pramipexole is used clinically ( see below ), its D 3-preferring receptor binding profile has made it a popular tool compound for preclinical research.
- Chemical biology cannot continue to overlook the existence of polypharmacology and it urge to become a more holistic discipline that looks at the use of tool compounds from a systems perspective
- Spiro compounds are present throughout the natural world, some cases of which have been exploited to provide tool compounds for biomedical study and to serve as scaffolds for the design of therapeutic agents with novel shapes.
- It's difficult to find tool compound in a sentence. 用tool compound造句挺難的
- Many natural products, such as curcumin, are hits in almost any assay in which they are tested, are not useful tool compounds, and are classified by medicinal chemists as " pan-assay interference compounds ".
- "' 7-Chlorokynurenic acid "'( "'7-CKA "') is a tool compound that acts as a potent and selective noncompetitive antagonist of the glycine site of the NMDA receptor.
- The use of film as a consciousness-raising tool compounds the money problem by scaring off a public that knows the world's woes and just wants some fun, said Barry Ronge, the film critic for The Star newspaper of South Africa.
- While it has never been approved for medical use it is a highly valuable tool compound for basic research to identify neurobiological mechanisms that are based on a dopamine D2-linked ( vs . D1, D3, D4, and D5-linked ) mechanism of action.
- Carpanone itself is limited in its pharmacologic and biologic activities, but related analogs arrived at by variations of the Brophy-Chapman approach have shown activities as tool compounds relevant to mammalian exocytosis and vesicular traffic, and provided therapeutic " hits " in antiinfective, antihypertensive, and hepatoprotective areas.
- Tool compounds are also important reagents in biology; they are small molecules or biochemicals like siRNA or antibodies that are known to affect a given biomolecule-for example a drug target-but are unlikely to be useful as drugs themselves, and are often starting points in the drug discovery process.
- In 2006, in the course of acquiring an HDAC-focused program from Celera after its own initial discovery program had failed, Pharmacyclics also picked up Celera's small molecule BTK inhibitor discovery program for $ 2M in cash and $ 1M in stock and named the tool compound PCI-32765.